1. Most Aneuploids arise by nondisjunction, a failure of homologous chromosomes to separate at meiosis.

2. Aneuploidy, also called nondisjunction, is the unequal distribution of chromosomes to daughter cells during cell division. It is usually caused by an interference with the structure or function of the mitotic spindle (made of proteins), which is responsible for separation …

3. B's are of two types: metacentric and acrocentric and are associated with three types of abnormalities: (i) failure of the A chromosomes to move to the poles at anaphase I; (ii) nondisjunction of some A chromosomes at anaphase II; and (iii) the occurrence of tetraploid sporocytes.